Does the levelshifter on GPIO5/INTERRUPT have to be bidirectional?

On the XC111 there is a levelshifter (TXB0104PWR, reference designator N11) for GPIO5 that is bidirectional. The reason is that XC111 was designed to be as flexible as possible. However, GPIO5 (which is renamed INTERRUPT in the latest datasheet for A111) is only used as an interrupt from the sensor A111 to the host MCU. Thus it can be changed to a unidirectional component.